Southeast Asian countries present economic, cultural and political conditions that have varying effects on the reform and implementation of anti-corruption efforts in healthcare systems. The most common corrupt practices in the health systems of several of Southeast Asian countries are nepotism, mismanagement of resources, capture of the sector by pharmaceutical and medical providers, bribery and informal payments. Anti-corruption interventions in the medical and pharmaceutical sectors in the region have consisted of promoting integrity, transparency and accountability, quality control testing and social accountability. There is a lack of conclusive empirical evidences about the impact of anti-corruption interventions in the health sector in these countries.